Doel De betrokkenheid van supraspinale structuren bij de controle van passieve bewegingen is nog onvoldoende opgehelderd. Eerdere studies leverden elektromyografisch bewijs voor snelheids- en type-afhankelijke veranderingen in spieractiviteit. Op basis van eigenschappen van mechanoreceptoren, leeftijdsgerelateerde …

In many western countries informal care is conceived as the answer to the increasing care demand. Little is known how formal and informal caregivers collaborate in the context of an diverse ageing population. The aim of this study was to gain insight in how professionals’ perspectives regarding the collaboration …

Metacognition, the ability to reflect and regulate one's cognitive processes, has been shown to play a role in various aspects of life, particularly in academic settings. While important steps have been made in uncovering the neural basis of metacognition for highly specific domains (such as perceptual …

Nicotine is a well-known and highly addictive substance with complex effects on cognition, anxiety, and neurophysiology. Despite its short-term anxiolytic effects, this drug often exacerbates anxiety symptoms. It disrupts emotional regulation through its impact on the central nucleus of the amygdala …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Brain disorders, such as Alzheimer’s disease and epilepsy have been linked to an imbalance in excitatory and inhibitory (E/I) inputs in the brain. However, the molecular mechanisms underlying E/I balance and plasticity in the brain are largely unresolved. Inhibitory synapses have a strong impact on brain …

Given the substantial increase in children attending center-based childcare over the past decades, the consequences of center-based childcare for children’s development have gained more attention in developmental research. However, the relation between center-based childcare and children’s neurocognitive …

Introduction While principles of neuroplasticity and motor learning emphasise the potential of high dosage of physical rehabilitation in children and adolescents with acquired brain injury (ABI) during the subacute phase, we lack empirical evidence to demonstrate its impact in terms of meaningful outcomes. …

Inleiding: Jaarlijks houden 40.000 mensen blijvende beperkingen over na hersenletsel, waaronder een Cerebrovasculair Accident (CVA). Voor het herstel van CVA-patiënten wordt bij Roessingh Centrum voor Revalidatie spiegeltherapie ingezet middels een protocol. Het doel is om een advies op te stellen voor …

Background & aims: Accurate diagnosis of sarcopenia requires evaluation of muscle quality, which refers to the amount of fat infiltration in muscle tissue. In this study, we aim to investigate whether we can independently predict mortality risk in transcatheter aortic valve implantation (TAVI) patients, …