Background: after hospitalisation for cardiac disease, older patients are at high risk of readmission and death. Objective: the cardiac care bridge (CCB) transitional care programme evaluated the impact of combining case management, disease management and home-based cardiac rehabilitation (CR) on hospital …

Background: Early identification of older cardiac patients at high risk of readmission or mortality facilitates targeted deployment of preventive interventions. In the Netherlands, the frailty tool of the Dutch Safety Management System (DSMS-tool) consists of (the risk of) delirium, falling, functional …

Objective: To study the effects of a comprehensive secondary prevention programme on weight loss and to identify determinants of weight change in patients with coronary artery disease (CAD). Methods: We performed a secondary analysis focusing on the subgroup of overweight CAD patients (BMI ≥27 kg/m2) …

IL22 is an important cytokine involved in the intestinal defense mechanisms against microbiome. By using ileum-derived organoids, we show that the expression of anti-microbial peptides (AMPs) and anti-viral peptides (AVPs) can be induced by IL22. In addition, we identified a bacterial and a viral route, …

In September 2017, the Lectorates LEAN & Worldclass Performance and Automotive Research of the HAN University of Applied Science, together with a consortium of (SME) industry partners, started the research project ‘Workshop on the Move’. The project is the search for the answer to the question as to …

Achtergrond In de psychiatrie zijn er nog té weinig aandacht voor en kennis over lichte verstandelijke beperking (lvb). Agressieproblemen komen regelmatig voor bij patiënten met een lvb die in de ggz behandeld worden en/of opgenomen zijn. Doel Verhelderen van achtergronden van agressieproblemen en adviezen …

When teaching grammar, one of the biggest challenges teachers face is how to make their students achieve conceptual understanding. Some scholars have argued that metaconcepts from theoretical linguistics should be used to pedagogically and conceptually enrich traditional L1 grammar teaching, generating …

In dit onderzoek wordt er onderzoek gedaan naar het ontwerpen in Cross laminated timber. Er wordt nagegaan hoe hoog er gebouwd kan worden in CLT met schroefverbindingen die veelal worden toegepast.

Tablets lijken de nieuwe hype in het basisonderwijs. Ze bieden nieuwe mogelijkheden: met adaptieve programma’s kunnen leerlingen op hun eigen niveau werken en zien ze direct of hun antwoorden goed zijn. Aan de hand van de resultaten kunnen programma’s de moeilijkheidsgraad van de vervolgopgaven bepalen. …

Objectives Meta-analyses using individual patient data (IPD) rather than aggregated data are increasingly applied to analyze sources of heterogeneity between trials and have only recently been applied to unravel multicomponent, complex interventions. This study reflects on methodological challenges …